Document Detail

Drug interactions in hypertension.
MedLine Citation:
PMID:  3280485     Owner:  NLM     Status:  MEDLINE    
Interactions between drugs and antihypertensive agents can result in either increased or decreased antihypertensive effects. These interactions may be pharmacokinetic or pharmacodynamic in type, resulting in either altered plasma drug concentrations or altered drug effects at similar plasma concentrations. Drugs may limit the absorption of antihypertensive agents, alter their metabolism through either enzyme inhibition or induction, or change renal excretion. In addition, by altering cardiovascular and volume homeostasis, changes in antihypertensive response may be produced.
A J Wood
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Hypertension     Volume:  11     ISSN:  0194-911X     ISO Abbreviation:  Hypertension     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-05-06     Completed Date:  1988-05-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  II1-3     Citation Subset:  IM    
Department of Medicine, Vanderbilt University, School of Medicine, Nashville, TN 37232.
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MeSH Terms
Antihypertensive Agents / pharmacology
Drug Interactions*
Hypertension / drug therapy*
Life Style
Grant Support
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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