Document Detail

Drug insight: Statin use in the elderly.
MedLine Citation:
PMID:  16729010     Owner:  NLM     Status:  MEDLINE    
The elderly represent a notable proportion of patients who present with myocardial infarction or acute coronary syndromes. This subgroup of patients also experiences a higher incidence of adverse outcomes than younger age-groups, and, therefore, has more to gain from effective, evidence-based therapies. The efficacy of statins in secondary cardiovascular disease prevention is firmly established. The starting of therapy soon after an acute coronary event has been shown to provide added benefit. Uncertainties about the effectiveness of statins in the elderly, however, have resulted in their underuse in this population. In this review we evaluate the evidence for statin use in this important and increasingly large group of patients.
O Christopher Raffel; Harvey D White
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nature clinical practice. Cardiovascular medicine     Volume:  3     ISSN:  1743-4297     ISO Abbreviation:  -     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-26     Completed Date:  2006-08-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101226507     Medline TA:  Nat Clin Pract Cardiovasc Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  318-28     Citation Subset:  IM    
Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
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MeSH Terms
Aged, 80 and over
Cholesterol, LDL / blood
Coronary Disease / blood,  drug therapy*,  economics,  prevention & control
Cost-Benefit Analysis
Drug Utilization
Health Services for the Aged / economics*
Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects,  economics,  therapeutic use*
Meta-Analysis as Topic
Middle Aged
Myocardial Infarction / blood,  drug therapy*,  economics,  prevention & control
Patient Compliance
Physician's Practice Patterns*
Practice Guidelines as Topic
Randomized Controlled Trials as Topic
Recurrence / prevention & control
Risk Assessment
Reg. No./Substance:
0/Cholesterol, LDL; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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