| Drug-induced methaemoglobinaemia following elective coronary artery bypass grafting. | |
| | |
MedLine Citation:
|
PMID: 17567353 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Dapsone can alter the oxygen carrying capacity of haemoglobin. Some patients are more susceptible to these effects because of genetic factors, comorbidities or peri-operative factors such as anaemia. We present a 57-year-old lady who underwent elective coronary artery bypass grafting. Deterioration in neurological and respiratory condition prompted a review of her drug treatment. A combination of long-term dapsone therapy, co-existing cardiac and respiratory disease, postoperative anaemia and renal impairment contributed to her decompensation, despite a relatively low level of methaemoglobin. Successful management included stopping dapsone therapy, supportive care and administration of ascorbic acid. |
| | |
Authors:
|
A Choi; A Sarang |
Related Documents
:
|
11335183 - Effects of temperature and air pollutants on cardiovascular and respiratory diseases fo... 895593 - Acute pulmonary failure: treatment with extracorporeal oxygenation. 12869173 - Pathology-related troponin i release and clinical outcome after pediatric open heart su... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Anaesthesia Volume: 62 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 2007 Jul |
Date Detail:
|
Created Date: 2007-06-14 Completed Date: 2007-07-24 Revised Date: 2007-11-27 |
Medline Journal Info:
|
Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: England |
Other Details:
|
Languages: eng Pagination: 737-40 Citation Subset: AIM; IM |
Affiliation:
|
Broomfield Hospital, Chelmsford CM1 7ET, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anti-Inflammatory Agents, Non-Steroidal
/
adverse effects* Antioxidants / therapeutic use Ascorbic Acid / therapeutic use Coronary Artery Bypass* Dapsone / adverse effects* Female Humans Hypoxia, Brain / chemically induced Methemoglobinemia / chemically induced*, drug therapy Middle Aged Postoperative Complications* |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Antioxidants; 50-81-7/Ascorbic Acid; 80-08-0/Dapsone |
| Comments/Corrections | |
Comment In:
|
Anaesthesia. 2007 Nov;62(11):1188
[PMID:
17924910
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Successful use of pharyngeal pulse oximetry with the oropharyngeal airway in severely shocked patien...
Next Document: Caudal anaesthesia as a treatment for penile ischaemia following circumcision.