| Drug-induced cardiovascular disorders. | |
| | |
MedLine Citation:
|
PMID: 17722970 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
As the variety and range of pharmaceutical agents available to the medical profession continues to expand, one unavoidable effect will be an increase in drug-induced disease, including cardiovascular disorders. However, given the high rates of cardiovascular disease and prevalence of recognised cardiovascular risk factors in the population, it is sometimes impossible to conclusively attribute any individual patients' ill health to one particular drug. As a result, the relationship between drugs and cardiovascular disease is often difficult to quantify. This review discusses specific forms of drug-induced cardiovascular disease such as heart failure, left ventricular systolic dysfunction, hypertension and arrhythmia. Suspected culprit drugs for all disorders are highlighted. Specific attention is given to certain drug groups with a strong association with one or more forms of cardiovascular disease: these include anthracyclines, antipsychotics, NSAIDs and cyclo-oxygenase 2 inhibitors. Additionally, advice is offered on how physicians might distinguish drug-induced cardiovascular disorders from other aetiologies. |
| | |
Authors:
|
C Aengus Murphy; Henry J Dargie |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Drug safety : an international journal of medical toxicology and drug experience Volume: 30 ISSN: 0114-5916 ISO Abbreviation: Drug Saf Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-08-28 Completed Date: 2008-01-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9002928 Medline TA: Drug Saf Country: New Zealand |
Other Details:
|
Languages: eng Pagination: 783-804 Citation Subset: IM |
Affiliation:
|
Cardiology Department, Western Infirmary, Glasgow, UK. aengus.murphy@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cardiovascular Diseases
/
chemically induced* Humans Pharmaceutical Preparations / adverse effects* |
| Chemical | |
Reg. No./Substance:
|
0/Pharmaceutical Preparations |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Benefit-risk assessment of nesiritide in the treatment of acute decompensated heart failure.
Next Document: Clinical pattern of zileuton-associated liver injury: results of a 12-month study in patients with c...