Document Detail

'Drug holidays' in the treatment of Parkinson's disease. A brief review.
MedLine Citation:
PMID:  3888135     Owner:  NLM     Status:  MEDLINE    
"Drug holiday," the withdrawal of levodopa for a variable period of time, is a controversial method of treating patients with Parkinson's disease who have levodopa-related complications. Only four studies have been published in which patients were observed for one year or longer. Although it is extremely beneficial for some patients, this treatment provides a sustained one-year benefit for only a minority of patients.
J H Friedman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of internal medicine     Volume:  145     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-06-06     Completed Date:  1985-06-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  913-5     Citation Subset:  AIM; IM    
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MeSH Terms
Drug Administration Schedule
Follow-Up Studies
Levodopa / administration & dosage*
Parkinson Disease / drug therapy*,  physiopathology
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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