Document Detail


Drug-eluting stents in peripheral vascular disease: eliminating restenosis.
MedLine Citation:
PMID:  14647877     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transcatheter endovascular therapy for peripheral atherosclerotic disease has become more popular. In general, good results have been reported in focal aortoiliac disease. However, the long-term patency of angioplasty in longer, more distal lesions has been less satisfactory. Stenting has not been shown to improve long-term patency compared to angioplasty alone. Drug-eluting stents have shown promise in preventing coronary restenosis, and preliminary results in peripheral arterial disease are encouraging. This review article will discuss the current status of endovascular therapy of aortoiliac and femoropopliteal atherosclerotic disease, the theoretic and experimental basis for the use of drug-eluting stents, and the preliminary results in human studies.
Authors:
Sharif H Ellozy; Alfio Carroccio
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Mount Sinai journal of medicine, New York     Volume:  70     ISSN:  0027-2507     ISO Abbreviation:  Mt. Sinai J. Med.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-03     Completed Date:  2004-01-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0241032     Medline TA:  Mt Sinai J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  417-9     Citation Subset:  IM    
Affiliation:
Department of Surgery, Mount Sinai School of Medicine, One East 100th Street, New York, NY 10029, USA. sharif.ellozy@msnyuhealth.org
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MeSH Terms
Descriptor/Qualifier:
Angiogenesis Inhibitors / administration & dosage
Anti-Inflammatory Agents / administration & dosage
Arterial Occlusive Diseases / prevention & control*
Coronary Restenosis / prevention & control
Drug Delivery Systems*
Humans
Immunosuppressive Agents / administration & dosage
Peripheral Vascular Diseases / drug therapy*
Prosthesis Design
Recurrence*
Sirolimus / administration & dosage
Stents*
Vascular Patency
Chemical
Reg. No./Substance:
0/Angiogenesis Inhibitors; 0/Anti-Inflammatory Agents; 0/Immunosuppressive Agents; 53123-88-9/Sirolimus

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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