| Drug-eluting stent for the treatment of symptomatic vertebral origin stenosis: Long-term results. | |
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MedLine Citation:
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PMID: 20888236 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Atherosclerotic stenosis originating from the vertebral artery (VA) is a well-known cause of stroke in the posterior circulation. Stent-assisted angioplasty using a bare metal stent is safe but used in a limited number of patients due to high rates of in-stent restenosis (ISR). A drug-eluting stent (DES) is an alternative for reducing ISR after stenting for atherosclerotic stenosis. We report the technical feasibility and mid to long-term clinical and angiographic outcomes after stenting with a DES in vertebral origin stenosis. This retrospective study included 47 consecutive patients treated with DES for vertebral origin stenosis. The demographics, indications for treatment, procedural technique, clinical and radiographical follow-up results were reviewed. The technical success rate was 100% without any complications. Postprocedure residual stenosis was 8.6% (range=0-12%). All patients were followed up clinically for a mean of 28.3 months (range=12-68months), and two patients (4.2%) had recurrent stroke in stented-vessel territories at 5 and 17 months after the procedure, respectively. Digital subtraction angiography was performed at follow-up in 38 patients (80.9%) at a mean of 16.3 months (range=6-48months) and showed two patients with ISR (5.3%) and four stent fractures (10.5%). One asymptomatic ISR was related to stent fracture. DES for vertebral origin stenosis are safe and effective with an acceptable lower ISR rate. However, stent fracture may be a potential complication and requires long-term follow-up. |
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Authors:
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Xinpu Chen; Qinghai Huang; Bo Hong; Yongwei Zhang; Yi Xu; Jianmin Liu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Volume: 18 ISSN: 1532-2653 ISO Abbreviation: J Clin Neurosci Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9433352 Medline TA: J Clin Neurosci Country: Scotland |
Other Details:
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Languages: eng Pagination: 47-51 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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