Document Detail


Drug-eluting stent implantation for acute myocardial infarction during pregnancy with use of glycoprotein IIb/IIIa inhibitor, aspirin and clopidogrel.
MedLine Citation:
PMID:  18460716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute myocardial infarction (AMI) during pregnancy, though rare, is nevertheless associated with a high mortality rate ranging from 37-50%. Percutaneous coronary intervention (PCI) with stenting is considered to be one of the more challenging therapeutic strategies in the management of AMI during pregnancy. We report a case of a 44-year-old pregnant woman who presented with an AMI. She underwent PCI using a drug-eluting stent (DES) with eptifibatide, aspirin and clopidogrel without complications, and later delivered a healthy infant at 36 weeks of gestation. With a tendency towards an increased proportion of births by older women, AMI during pregnancy may become more frequent. The risks and benefits of DES placement and the use of adjuvant antiplatelet therapy for coronary interventions during pregnancy are discussed here.
Authors:
Rafid Fayadh Al-Aqeedi; Abdulrahman D Al-Nabti
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  20     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-07     Completed Date:  2008-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E146-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology and Cardiac Surgery, Hamad Medical corporation, P.O.Box 3050, Doha, Qatar. aalnabti@hmc.org.qa
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MeSH Terms
Descriptor/Qualifier:
Aspirin / administration & dosage*
Coronary Angiography
Drug-Eluting Stents*
Electrocardiography
Female
Humans
Myocardial Infarction / drug therapy*,  radiography,  surgery
Platelet Aggregation Inhibitors / administration & dosage*
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Pregnancy
Pregnancy Complications, Cardiovascular / drug therapy*,  radiography,  surgery
Prosthesis Implantation
Ticlopidine / administration & dosage,  analogs & derivatives*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Platelet Aggregation Inhibitors; 0/Platelet Glycoprotein GPIIb-IIIa Complex; 50-78-2/Aspirin; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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