Document Detail


Drug discovery in pharmaceutical industry: Productivity challenges and trends.
MedLine Citation:
PMID:  22627006     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Low productivity, rising R&D costs, dissipating proprietary products, and dwindling pipelines are driving the pharmaceutical industry to unprecedented challenges and scrutiny. In this article I reflect on the current status of the pharmaceutical industry and reasons for continued low productivity. An emerging 'symbiotic model of innovation', that addresses underlying issues in drug failure and attempts to narrow gaps in current drug discovery processes, is discussed to boost productivity. The model emphasizes partnerships in innovation to deliver quality products in a cost-effective system. I also discuss diverse options to build a balanced research portfolio with higher potential for persistent delivery of drug molecules.
Authors:
Ish Khanna
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-21
Journal Detail:
Title:  Drug discovery today     Volume:  -     ISSN:  1878-5832     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9604391     Medline TA:  Drug Discov Today     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Ltd.
Affiliation:
Kareus Therapeutics, 6045 Atlantic Boulevard, Norcross, GA-30071, USA.
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