Document Detail

Drug-coated balloons and their place in treating peripheral arterial disease.
MedLine Citation:
PMID:  23278227     Owner:  NLM     Status:  In-Data-Review    
Drug-coated balloons (DCB) have emerged as an additional treatment option for managing restenosis in lesions of the superficial femoral artery and of the infrapopliteal arterial bed. Relatively limited data are available on the use of DCB in these lesions, but scientific evidence is mounting. In five randomized controlled trials, late lumen loss 6 months after the intervention was found to be markedly lower in patients treated with paclitaxel-coated balloons (PCB) compared with uncoated balloons. Different types of PCB are currently on the market. It remains to be seen how different coatings affect the performance of PCB and clinical outcome. Long-term results are also awaited. In this review, the authors describe the components of DCB and how they affect performance. Then, the authors provide an overview of clinical results obtained with PCB in the superficial femoral artery and below the knee, and finally the article gives an outlook on the future of DCB in peripheral arterial disease.
Beatrix Schnorr; Thomas Albrecht
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of medical devices     Volume:  10     ISSN:  1745-2422     ISO Abbreviation:  Expert Rev Med Devices     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230445     Medline TA:  Expert Rev Med Devices     Country:  England    
Other Details:
Languages:  eng     Pagination:  105-14     Citation Subset:  IM    
Department of Radiology, Experimental Radiology, Charité, University Hospital, Berlin, Germany.
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