Document Detail


Drug carriers for oral delivery of peptides and proteins: accomplishments and future perspectives.
MedLine Citation:
PMID:  23343163     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Effective formulation for peptide and protein delivery through the oral route has always been the critical effort with the advent of biotechnology. Stability, enzymatic degradation and ineffective absorption are common difficulties found for conventional dosage forms. As a result, new drug-delivery approaches are used to circumvent these limitations and enhance effective oral drug delivery. Some of these technologies have reached late stages of clinical trials and promising results will be available in the near future. This review covers, in general, the recent carriers reported in literature.
Authors:
Catarina Pinto Reis; Catarina Silva; Nuno Martinho; Catarina Rosado
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Therapeutic delivery     Volume:  4     ISSN:  2041-5990     ISO Abbreviation:  Ther Deliv     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101538870     Medline TA:  Ther Deliv     Country:  England    
Other Details:
Languages:  eng     Pagination:  251-65     Citation Subset:  IM    
Affiliation:
Universidade Lusófona (CBIOS - Laboratory of Nanoscience & Biomedical Nanotechnology), Campo Grande 376, 1749-024 Lisboa, Portugal.
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