Document Detail

Drug addiction in pregnancy and the neonate.
MedLine Citation:
PMID:  1266895     Owner:  NLM     Status:  MEDLINE    
Drug addiction during pregnancy has been managed in two ways: the detoxification program and the methadone-maintenance treatment program. In the detoxification program, there have been few complications for the mother and child except for low birth weight, meconium-stained amniotic fluid, and an increase in breech presentation. The methadone-maintenance treatment program at this time is the most satisfactory approach to the treatment of heroin addiction. The complications of pregnancy in this program are similar to those of the average obstetric population. Low birth weight at term is still frequent for those on methadone maintenance. The problem of multiple drug abuse, including heroin, cocaine, alcohol, tranquilizers, and amphetamines, requires more attention. The characteristics of the withdrawal syndrome and its treatment in infants are described. Excessive weight loss and irritability are commin in these infants. Of the many drugs available for the treatment of the newborn withdrawal syndrome, diazepam is currently favored. The long-term effects of intrauterine drug exposure, the withdrawal syndrome, and treatment are generally unknown. Schedules for management of adult narcotic, alcohol, and barbiturate abuse and newborn narcotic withdrawal are suggested.
G Blinick; R C Wallach; E Jerez; B D Ackerman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  125     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1976 May 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  135-42     Citation Subset:  AIM; IM    
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MeSH Terms
Alcoholic Intoxication / drug therapy
Birth Weight
Diazepam / therapeutic use
Heroin Dependence / drug therapy
Infant, Newborn
Infant, Newborn, Diseases / drug therapy,  etiology*,  physiopathology
Methadone / administration & dosage,  therapeutic use*
Pregnancy Complications / drug therapy*
Substance Withdrawal Syndrome / drug therapy*
Substance-Related Disorders / complications,  drug therapy*
Sudden Infant Death / etiology
Reg. No./Substance:
439-14-5/Diazepam; 76-99-3/Methadone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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