Document Detail

Drosophila virilis has long and highly polymorphic microsatellites.
MedLine Citation:
PMID:  11070052     Owner:  NLM     Status:  MEDLINE    
Comparative genomics is a powerful approach to inference of the dynamics of genome evolution. Most information about the evolution of microsatellites in the genus Drosophila has been obtained from Drosophila melanogaster. For comparison, we collected microsatellite data for the distantly related species Drosophila virilis. Screening about 0.5 Mb of nonredundant genomic sequence from GenBank, we identified 239 dinucleotide microsatellites. On average, D. virilis dinucleotides were significantly longer than D. melanogaster microsatellites (7.69 repeats vs. 6.75 repeats). Similarly, direct cloning of microsatellites resulted in a higher mean repeat number in D. virilis than in D. melanogaster (12.7 repeats vs. 12.2 repeats). Characterization of 11 microsatellite loci mapping to division 40-49 on the fourth chromosome of D. virilis indicated that D. virilis microsatellites are more variable than those of D. melanogaster.
C Schlötterer; B Harr
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Molecular biology and evolution     Volume:  17     ISSN:  0737-4038     ISO Abbreviation:  Mol. Biol. Evol.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2000-12-01     Completed Date:  2001-03-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8501455     Medline TA:  Mol Biol Evol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1641-6     Citation Subset:  IM    
Institut für Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Vienna, Austria.
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MeSH Terms
DNA / genetics
Databases, Factual
Drosophila / genetics*
Drosophila melanogaster / genetics
Evolution, Molecular
Genetic Variation
Microsatellite Repeats / genetics*
Polymorphism, Genetic
Species Specificity
Reg. No./Substance:

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