| The Drosophila dunce locus: learning and memory genes in the fly. | |
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MedLine Citation:
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PMID: 1653476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The dunce gene, one of several genes critical for normal learning and memory in Drosophila, is organized in a complex and bizarre way, with enormous introns containing several other unrelated genes. Recent studies have focused on the spatial expression pattern of the product, cAMP phosphodiesterase, and have provisionally identified the mushroom bodies as important sites of action of dunce within adult brain. In addition, the recent cloning and characterization of dunce counterparts from mammals has revealed that these too may participate in animal behavior and, in particular, in the regulation of mood. |
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Authors:
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R L Davis; B Dauwalder |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Trends in genetics : TIG Volume: 7 ISSN: 0168-9525 ISO Abbreviation: Trends Genet. Publication Date: 1991 Jul |
Date Detail:
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Created Date: 1991-10-08 Completed Date: 1991-10-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8507085 Medline TA: Trends Genet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 224-9 Citation Subset: IM |
Affiliation:
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Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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3',5'-Cyclic-AMP Phosphodiesterases
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genetics*,
metabolism Animals Drosophila melanogaster / genetics*, physiology Gene Expression Regulation, Enzymologic Humans Learning* |
| Chemical | |
Reg. No./Substance:
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EC 3.1.4.17/3',5'-Cyclic-AMP Phosphodiesterases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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