Document Detail


Drop episodes in Coffin-Lowry syndrome: exaggerated startle responses treated with clonazepam.
MedLine Citation:
PMID:  9744638     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 16-year-old girl had fully manifested Coffin-Lowry syndrome and drop episodes. Her drop episodes were precipitated by sudden unexpected tactile or auditory stimuli associated with the electrostatic circumstances in her leg muscles immediately after the stimuli. Studies revealed that her drop episode symptom was an unusual type of startle response and that it may be associated with Coffin-Lowry syndrome.
Authors:
M Nakamura; T Yamagata; M Y Momoi; T Yamazaki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  19     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-12-04     Completed Date:  1998-12-04     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  148-50     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Jichi Medical School, Tochigi, Japan.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / drug therapy*,  physiopathology*
Adult
Anticonvulsants / therapeutic use*
Clonazepam / therapeutic use*
Electroencephalography
Electromyography
Facial Bones / radiography
Facies
Female
Hand Deformities, Congenital / complications,  radiography
Humans
Leg / physiopathology*
Mental Retardation / complications
Muscle, Skeletal / drug effects,  physiopathology*
Startle Reaction / drug effects*
Syndrome
Chemical
Reg. No./Substance:
0/Anticonvulsants; 1622-61-3/Clonazepam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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