Document Detail


Driving biochemical discovery with quantitative proteomics.
MedLine Citation:
PMID:  20880711     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Proteomic analysis of biological samples plays an increasing role in modern research. Although the application of proteomics technologies varies across many disciplines, proteomics largely is a tool for discovery that then leads to novel hypotheses. In recent years, new methods and technologies have been developed and applied in many areas of proteomics, and there is a strong push towards using proteomics in a quantitative manner. Indeed, mass spectrometry-based, quantitative proteomics approaches have been applied to great success in a variety of biochemical studies. In particular, the use of quantitative proteomics provides new insights into protein complexes and post-translational modifications and leads to the generation of novel insights into these important biochemical systems.
Authors:
Michael P Washburn
Publication Detail:
Type:  Journal Article     Date:  2010-09-27
Journal Detail:
Title:  Trends in biochemical sciences     Volume:  36     ISSN:  0968-0004     ISO Abbreviation:  Trends Biochem. Sci.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610674     Medline TA:  Trends Biochem Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  170-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Stowers Institute for Medical Research, Kansas City, 1000 E. 50(th) St., MO 64110, USA; Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
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