Document Detail

Drinking capacity and severity of dyspeptic symptoms during a water load test after Nissen fundoplication.
MedLine Citation:
PMID:  17406836     Owner:  NLM     Status:  MEDLINE    
Up to 30% of subjects undergoing Nissen fundoplication develop dyspeptic symptoms. Previous studies using the water load test have shown that functional dyspepsia patients have a diminished drinking capacity due to increased visceral sensitivity. Here we investigate drinking capacity and severity of symptoms in 9 patients with dyspeptic symptoms after fundoplication, 9 patients without symptoms after surgery, 18 functional dyspepsia patients, and 18 controls. The water load test was performed by having subjects drinking room-temperature tap water at a predetermined rate of 15 ml/min. The presence and severity of symptoms during the test were evaluated every 5 min using a Likert scale. We found that patients with dyspeptic symptoms after fundoplication had a significantly lower drinking capacity and higher symptoms scores than controls (P<0.05) but values similar to those of functional dyspepsia patients (P>0.05). In contrast, drinking capacity in patients without symptoms after surgery was similar to that in controls (P>0.05). These findings suggest that, as in functional dyspepsia, severe dyspeptic symptoms after Nissen fundoplication are associated with an impaired drinking capacity, reflecting visceral hypersensitivity or impaired gastric accommodation or both.
Jose María Remes-Troche; Aldo Montaño-Loza; Julio César Martínez; Miguel Herrera; Miguel Angel Valdovinos-Díaz
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Publication Detail:
Type:  Journal Article     Date:  2007-04-04
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  52     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-09-06     Completed Date:  2007-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2850-7     Citation Subset:  AIM; IM    
Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Sección XVI, CP 14000, México, DF, México.
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MeSH Terms
Drinking / physiology*
Dyspepsia / etiology,  physiopathology*
Fundoplication / adverse effects*
Gastroesophageal Reflux / surgery
Postoperative Complications
Severity of Illness Index
Water / diagnostic use*
Reg. No./Substance:

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