| Drinking capacity and severity of dyspeptic symptoms during a water load test after Nissen fundoplication. | |
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MedLine Citation:
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PMID: 17406836 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Up to 30% of subjects undergoing Nissen fundoplication develop dyspeptic symptoms. Previous studies using the water load test have shown that functional dyspepsia patients have a diminished drinking capacity due to increased visceral sensitivity. Here we investigate drinking capacity and severity of symptoms in 9 patients with dyspeptic symptoms after fundoplication, 9 patients without symptoms after surgery, 18 functional dyspepsia patients, and 18 controls. The water load test was performed by having subjects drinking room-temperature tap water at a predetermined rate of 15 ml/min. The presence and severity of symptoms during the test were evaluated every 5 min using a Likert scale. We found that patients with dyspeptic symptoms after fundoplication had a significantly lower drinking capacity and higher symptoms scores than controls (P<0.05) but values similar to those of functional dyspepsia patients (P>0.05). In contrast, drinking capacity in patients without symptoms after surgery was similar to that in controls (P>0.05). These findings suggest that, as in functional dyspepsia, severe dyspeptic symptoms after Nissen fundoplication are associated with an impaired drinking capacity, reflecting visceral hypersensitivity or impaired gastric accommodation or both. |
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Authors:
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Jose María Remes-Troche; Aldo Montaño-Loza; Julio César Martínez; Miguel Herrera; Miguel Angel Valdovinos-Díaz |
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Publication Detail:
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Type: Journal Article Date: 2007-04-04 |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 52 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-09-06 Completed Date: 2007-10-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 2850-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Sección XVI, CP 14000, México, DF, México. chemaremes@hotmail.com |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Drinking / physiology* Dyspepsia / etiology, physiopathology* Female Fundoplication / adverse effects* Gastroesophageal Reflux / surgery Humans Male Postoperative Complications Prognosis Severity of Illness Index Water / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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