Document Detail

Drinking water fluoride and blood pressure? An environmental study.
MedLine Citation:
PMID:  21484404     Owner:  NLM     Status:  MEDLINE    
The relationship between intakes of fluoride (F) from drinking water and blood pressure has not yet been reported. We examined the relationship of F in ground water resources (GWRs) of Iran with the blood pressure of Iranian population in an ecologic study. The mean F data of the GWRs (as a surrogate for F levels in drinking water) were derived from a previously conducted study. The hypertension prevalence and the mean of systolic and diastolic blood pressures (SBP & DBP) of Iranian population by different provinces and genders were also derived from the provincial report of non-communicable disease risk factor surveillance of Iran. Statistically significant positive correlations were found between the mean concentrations of F in the GWRs and the hypertension prevalence of males (r = 0.48, p = 0.007), females (r = 0.36, p = 0.048), and overall (r = 0.495, p = 0.005). Also, statistically significant positive correlations between the mean concentrations of F in the GWRs and the mean SBP of males (r = 0.431, p = 0.018), and a borderline correlation with females (r = 0.352, p = 0.057) were found. In conclusion, we found the increase of hypertension prevalence and the SBP mean with the increase of F level in the GWRs of Iranian population.
Hassan Amini; Seyed Mahmood Taghavi Shahri; Mohamad Amini; Majid Ramezani Mehrian; Yaser Mokhayeri; Masud Yunesian
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Publication Detail:
Type:  Journal Article     Date:  2011-04-12
Journal Detail:
Title:  Biological trace element research     Volume:  144     ISSN:  1559-0720     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-19     Completed Date:  2012-04-27     Revised Date:  2013-01-16    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  157-63     Citation Subset:  IM    
Department of Environmental Health Engineering, Tehran University of Medical Sciences, Qods Street, PO Box 14155-6446, Tehran, Iran.
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MeSH Terms
Blood Pressure / drug effects*
Drinking Water / analysis*
Environmental Monitoring / methods*
Epidemiological Monitoring
Fluoridation / adverse effects*
Fluorides / analysis*
Groundwater / analysis
Hypertension / chemically induced,  epidemiology
Iran / epidemiology
Population Surveillance
Regression Analysis
Risk Factors
Sex Factors
Reg. No./Substance:
0/Drinking Water; 0/Fluorides
Comment In:
Biol Trace Elem Res. 2012 Dec;150(1-3):1-2   [PMID:  22918787 ]

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