Document Detail


Dramatic response of a patient with pregnancy induced idiopathic pulmonary arterial hypertension to sildenafil treatment.
MedLine Citation:
PMID:  20492398     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complications of pulmonary arterial hypertension (PAH). A patient diagnosed with IPAH after a successful full-term pregnancy and cesarean section with epidural anesthesia is presented. The postoperative course was complicated by progressive dyspnea, and lower limb edema. The outcome of treatment with sildenafil during puerperium was favorable in this patient. The clinical course was complicated by an unexpected spontaneous pregnancy after primary infertility.
Authors:
Gülten Taçoy; Numan Nadir Ekim; Atiye Cengel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  36     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-08-20     Revised Date:  2012-01-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  414-7     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Faculty of Medicine, Gazi University, Ankara, Turkey. gtacoy@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Hypertension, Pregnancy-Induced / drug therapy*
Hypertension, Pulmonary / drug therapy*
Piperazines / therapeutic use*
Pregnancy
Purines / therapeutic use
Sulfones / therapeutic use*
Treatment Outcome
Vasodilator Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Piperazines; 0/Purines; 0/Sulfones; 0/Vasodilator Agents; 139755-83-2/sildenafil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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