Document Detail


Draft genome sequence of Wickerhamomyces ciferrii NRRL Y-1031 F-60-10.
MedLine Citation:
PMID:  23193139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Wickerhamomyces ciferrii is a microorganism characterized by the production and secretion of large amounts of acetylated sphingoid bases, in particular tetraacetyl phytosphingosine. Here, we present the 15.90-Mbp draft genome sequence of W. ciferrii NRRL Y-1031 F-60-10 generated by pyrosequencing and de novo assembly. The draft genome sequence comprising 364 contigs in 150 scaffolds was annotated and covered 6,702 protein-coding sequences. This information will contribute to the metabolic engineering of this yeast to improve the yield and spectrum of acetylated sphingoid bases in biotechnological production.
Authors:
Jessica Schneider; Heiko Andrea; Jochen Blom; Sebastian Jaenicke; Christian Rückert; Christoph Schorsch; Rafael Szczepanowski; Mike Farwick; Alexander Goesmann; Alfred Pühler; Steffen Schaffer; Andreas Tauch; Tim Köhler; Karina Brinkrolf
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Eukaryotic cell     Volume:  11     ISSN:  1535-9786     ISO Abbreviation:  Eukaryotic Cell     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-29     Completed Date:  2013-05-09     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  101130731     Medline TA:  Eukaryot Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1582-3     Citation Subset:  IM    
Affiliation:
Institute for Genome Research and Systems Biology, Bielefeld University, Bielefeld, Germany.
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MeSH Terms
Descriptor/Qualifier:
Base Sequence
Contig Mapping
Databases, Genetic
Genome, Fungal*
Molecular Sequence Annotation
Molecular Sequence Data
Pichia / genetics*
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