Document Detail


Down syndrome in monochorionic twins.
MedLine Citation:
PMID:  19644615     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Down syndrome in monochorionic twins has rarely been reported. We report such a case diagnosed prenatally. Maternal serum screening was performed at 15 weeks for a twin pregnancy which indicated a risk of greater than 1:50 for Down syndrome. The review of early ultrasonography confirmed monochorionic twins. Amniocentesis at 17 weeks' gestation was performed on one of the twin sacs, which confirmed Down syndrome. A screening scan at 19 weeks' gestation showed isolated absent nasal bones in both twins. Termination of pregnancy was performed subsequently.
Authors:
I L Sin; T Y T Tan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  50     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-31     Completed Date:  2009-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  e264-7     Citation Subset:  IM    
Affiliation:
Raffles Women's Centre, Raffles Hospital, 585 North Bridge Road, #12-00, Singapore.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniocentesis
Amnion
Chorion*
Diseases in Twins
Down Syndrome / diagnosis*
Female
Humans
Pregnancy
Prenatal Diagnosis
Twins, Monozygotic
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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