Document Detail

Double spinal dysraphism. Report of three cases.
MedLine Citation:
PMID:  17465369     Owner:  NLM     Status:  MEDLINE    
The simultaneous presence of multiple spinal neural tube defects is unusual. There have been only a few of these cases reported in the literature. The authors report on three cases of double spina bifida cystica. One patient had two myelomeningoceles (MMCs) at the cervical and lumbosacral regions, one was noted to have both thoracolumbar and sacral defects, and the third presented with double MMCs at lumbar and lumbosacral levels. All three neonates in these cases underwent surgical treatment and ventriculoperitoneal (VP) shunt insertion for associated hydrocephalus. One child died at the age of 2 months despite a well-functioning VP shunt. The other two patients had no complications. Current models of neural tube closure do not thoroughly explain the mechanisms of multiple spinal dysraphism, but the multisite closure model provides a better understanding of caudal neural tube closure than other closure-site models.
Sepideh Keshavarzi; Farideh Nejat; Hadi Kazemi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  106     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-30     Completed Date:  2007-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  316-8     Citation Subset:  AIM; IM    
Department of Neurosurgery, Children's Medical Center, Tehran University of Medical Sciences, Iran.
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MeSH Terms
Infant, Newborn
Spina Bifida Cystica / pathology*,  radiography*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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