| Double-peaked high-pressure zone at the esophagogastric junction in controls and in patients with a hiatal hernia: a study using high-resolution manometry. | |
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MedLine Citation:
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PMID: 15387333 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The lower esophageal high-pressure zone (HPZ) consists of the intrinsic lower esophageal sphincter (LES) and the diaphragmatic sphincter. In patients with a hiatal hernia these constituents are separated. We performed high-resolution manometry of the esophagogastric HPZ in six controls, six patients with a small hernia, and six patients with a large hernia. Prevalence of a double-peak pressure profile of the HPZ was noted. Pressures and distances between the peaks were assessed. Prevalence of the double-peak profile was similar between patients with a small hernia and controls, but patients with a large hernia showed a higher prevalence with inspiration (P < 0.05) than the others. The distance between the two peaks was larger in patients with a large hernia (P < 0.05). In conclusion, high-resolution manometry makes it possible to distinguish the diaphragmatic pressure component from the LES. Two pressure peaks can be found both in hernia patients and in healthy volunteers. |
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Authors:
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A J Bredenoord; B L A M Weusten; S Carmagnola; A J P M Smout |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 49 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-09-24 Completed Date: 2004-11-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 1128-35 Citation Subset: AIM; IM |
Affiliation:
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Department of Gastroenterology, Sint Antonius Hospital, Nieuwegein, The Netherlands. a.bredenoord@antonius.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Esophagogastric Junction / physiology*, physiopathology* Female Hernia, Hiatal / physiopathology* Humans Male Manometry / methods* Middle Aged |
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