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Double jeopardy: Multi-modality imaging of monozygotic "twin cap" atherosclerosis.
MedLine Citation:
PMID:  25282686     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The investigation of asymptomatic but potentially vulnerable atherosclerosis is not yet a major focus for clinical Cardiologists. We have illustrated the contemporary investigation and treatment of such disease using a clinical case that involved monozygotic twins. One twin (T1) had unfortunately suffered a cardiac arrest whilst jogging and survived only due to bystander CPR and prompt defibrillation. His identical twin brother (T2), on subsequent investigation, harbours a compositionally identical lesion in a proximal coronary vessel that has not yet ruptured or provoked a clinical event. Following the presentation of both non-invasive and invasive images, we discuss the need for active suspicion and intensive treatment for those people with a 'genetic' risk of future myocardial infarction.
Authors:
Scott W Murray; Robert M Cooper; Clare Appleby; Caroline McCann; Sukumaran Binukrishnan; Maria D Radu; Rodney H Stables
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-30
Journal Detail:
Title:  Atherosclerosis     Volume:  237     ISSN:  1879-1484     ISO Abbreviation:  Atherosclerosis     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-10-5     Completed Date:  -     Revised Date:  2014-10-6    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  264-267     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
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