| Double isotope derivative dilution method for the determination of prostaglandin F and E type metabolites in urine. | |
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MedLine Citation:
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PMID: 341230 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This method was developed for the quantitative determination of the main ureinary metabolite (MUM) of prostaglandin (PG) F and E type in man or experimental animal. This method was based on the extraction of PG-MUM after addition of 3H-PG-MUM, the esterification with 14C-acetic anhydride and the separation and purification by column chromatography. Excretion values of adult men were PGF-MUM 1.46--15.01 microgram/8 hr (n=11), PGE-MUM 0.8*--15.42 microgram/8 hr; and with women, PGF-MUM 0.41--7.75 microgram/8 hr (n=11), PGE-MUM 0.60--11.39 microgram/8 hr. |
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Authors:
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Y Aizawa; K Yamada; M Hata |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Prostaglandins Volume: 14 ISSN: 0090-6980 ISO Abbreviation: Prostaglandins Publication Date: 1977 |
Date Detail:
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Created Date: 1978-03-29 Completed Date: 1978-03-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0320271 Medline TA: Prostaglandins Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1165-74 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chromatography, Gel Humans Indomethacin / pharmacology Prostaglandins E / urine* Prostaglandins F / urine* Radioisotope Dilution Technique / methods* |
| Chemical | |
Reg. No./Substance:
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0/Prostaglandins E; 0/Prostaglandins F; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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