| Double inversion recovery magnetic resonance imaging at 3 T: diagnostic value in hippocampal sclerosis. | |
| | |
MedLine Citation:
|
PMID: 21412105 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: : The objective of the study was to examine the utility of double inversion recovery (DIR) magnetic resonance imaging (MRI) using a 3-T magnetic resonance imager in the preoperative evaluation of hippocampal sclerosis (HS) in patients with mesial temporal lobe epilepsy. METHODS: : This retrospective study had institutional review board approval, and informed consent was obtained. Twelve patients with unilateral HS and 12 age-matched healthy control subjects were included. Imaging was performed using DIR, fluid-attenuated inversion recovery (FLAIR), and T2-weighted turbo spin-echo (T2 TSE) sequences vertical to the hippocampal axis. Quantitative assessment for hippocampus of the patients and control subjects was determined. Regions of interest (ROIs) were placed on bilateral hippocampi, and signal intensity was measured. The signal-to-noise ratio (SNR) of ipsilateral hippocampus, contrast ratio of ipsilateral-to-contralateral side, contrast-to-noise ratio (CNR), and asymmetry index of bilateral hippocampi were calculated and compared among the 3 sequences. Statistical analyses were performed with 1-way analysis of variance and Student t test. RESULTS: : On DIR images, HS demonstrated extremely high signal intensity. The hippocampi ipsilateral to the seizure focus showed significantly increased signal intensity, as compared with contralateral hippocampi and healthy subjects (F = 47.876, P < 0.001). The higher SNR of ipsilateral hippocampus on DIR was significant compared with the FLAIR and T2 TSE (P < 0.01). The CNR of bilateral hippocampi on DIR was also significantly higher than that on the FLAIR and T2 TSE (P < 0.01). However, compared with the FLAIR, no significant differences of contrast ratio and asymmetry index between bilateral hippocampi were observed on DIR. CONCLUSIONS: : Double inversion recovery brain imaging reveals characteristically extremely high signal intensity of hippocampus in patients with HS. Double inversion recovery images can describe HS with high SNR and CNR superior to conventional magnetic resonance sequences and can be valuable for the diagnosis of HS. |
| | |
Authors:
|
Qiong Li; Quan Zhang; Haoran Sun; Yunting Zhang; Renju Bai |
Related Documents
:
|
8737995 - Supramalleolar fatigue fractures of the tibia. 16218555 - A compartmental approach to the radiographic evaluation of soft-tissue calcifications. 15564155 - Prevertebral soft tissue measurements in thyroid enlargement: the value of lateral neck... 10975345 - Assessment of the quality of radiographs in 44 veterinary clinics in great britain. 22103585 - Bacteremia and mr-proanp changes in mild community-acquired pneumonia. 11284475 - On-off study of manganese administration to adult patients undergoing home parenteral n... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of computer assisted tomography Volume: 35 ISSN: 1532-3145 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2011 Mar-Apr |
Date Detail:
|
Created Date: 2011-03-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
|
Languages: eng Pagination: 290-3 Citation Subset: IM |
Affiliation:
|
From the *Department of Radiology, General Hospital of Tianjin Medical University; and †Department of Radiology, Pingjin Hospital, Medical College of the Chinese People's Armed Police Forces, Tianjin, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Separation of left and right lungs using 3-dimensional information of sequential computed tomography...
Next Document: High-Definition CT Gemstone Spectral Imaging of the Brain: Initial Results of Selecting Optimal Mono...