Document Detail

Double heterotopic pancreas and Meckel's diverticulum in a child: do they have a common origin?
MedLine Citation:
PMID:  20718198     Owner:  NLM     Status:  MEDLINE    
Heterotopic pancreatic tissue consists of normally differentiated pancreatic tissue without a real anatomic and vascular connection to the pancreas, whereas Meckel's diverticulum is one of the most important cause of lower gastrointestinal bleeding in children. Although heterotopic pancreatic tissue is related to various gastrointestinal diseases/malformations in both humans and animals, it is rarely associated with Meckel's diverticulum. Herein, we report a five-year old boy who presented with melena and hematochezia, which were discovered to be the result of Meckel's diverticulum. He also had multiple heterotopic pancreatic tissues in various parts of the gastrointestinal tract. The reason for this association is not known, but might involve some abnormalities of signaling molecules expressed in the development of the gastrointestinal tract and associated organs. In clinical practice, it is important to remember that Meckel's diverticulum and heterotopic pancreatic tissue might occur together or accompany various other gastrointestinal anomalies.
Gökhan Baysoy; Necati Balamtekin; Nuray Uslu; Afra Karavelioğlu; Beril Talim; Hasan Ozen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  52     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-08-19     Completed Date:  2010-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  336-8     Citation Subset:  IM    
Unit of Pediatric Gastroenterology, Hepatology and Nutrition, Hacettepe University Faculty of Medicine, Ankara, Turkey.
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MeSH Terms
Child, Preschool
Choristoma / pathology*
Gastrointestinal Diseases / pathology*
Gastrointestinal Tract / embryology
Meckel Diverticulum / embryology,  pathology*

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