| Double-blind crossover clinical pharmacology study comparing moxestrol (R 2858) and ethinyl estradiol in postmenopausal women. | |
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MedLine Citation:
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PMID: 338643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The potency of 5 migrogram moxestrol (R 2858). 11beta-methoxy-17alpha-ethinyl-estra-1,3,5-[10]-triene-3,17-diol, administered orally, was compared to that of 25 microgram ethinyl estradiol in a double-blind crossover clinical pharmacology study of six postmenopausal women. At these doses, both compounds increased the eosinophilic index and decreased serum LH and FSH levels. A marked effect on circulating prolactin was observed only during ethinyl estradiol treatment. |
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Authors:
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C Robyn; M Vekemans; M Rozencweig; D Chigot; J P Raynaud |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of clinical pharmacology Volume: 18 ISSN: 0091-2700 ISO Abbreviation: J Clin Pharmacol Publication Date: 1978 Jan |
Date Detail:
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Created Date: 1978-02-23 Completed Date: 1978-02-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0366372 Medline TA: J Clin Pharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 29-34 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Clinical Trials as Topic Double-Blind Method Eosinophils / drug effects Ethinyl Estradiol / analogs & derivatives*, pharmacology*, therapeutic use Female Follicle Stimulating Hormone / blood Humans Luteinizing Hormone / blood Menopause / drug effects* Middle Aged Prolactin / blood |
| Chemical | |
Reg. No./Substance:
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57-63-6/Ethinyl Estradiol; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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