| Double-Blind, Placebo-Controlled, Crossover Study of the Efficacy and Safety of Lisdexamfetamine Dimesylate in College Students With ADHD. | |
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MedLine Citation:
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PMID: 22166471 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: To evaluate stimulant medication on symptoms and functioning for college students with ADHD using double-blind, placebo-controlled, crossover design. Method: Participants included 24 college students with ADHD and 26 college students without psychopathology. Lisdexamfetamine dimesylate (LDX) was examined for ADHD participants over five weekly phases (no-drug baseline, placebo, 30-, 50-, and 70-mg LDX per day). Self-report rating scales of functioning and direct assessment of ADHD symptoms, verbal learning/memory, and adverse side effects were collected (baseline only for control students). Results: LDX was associated with large reductions in ADHD symptoms and improvement in executive functioning along with smaller effects for psychosocial functioning. Reduction in ADHD symptoms was found for 86.4% of participants; however, large differences in symptoms and executive functioning remained relative to controls. Conclusion: LDX is a safe, efficacious treatment for symptom relief in college students with ADHD. Research documenting medication effects on academic functioning and evaluating psychosocial/educational interventions is needed. (J. of Att. Dis. 2011; XX(X) 1-XX). |
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Authors:
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George J Dupaul; Lisa L Weyandt; Joseph S Rossi; Brigid A Vilardo; Sean M O'Dell; Kristen M Carson; Genevieve Verdi; Anthony Swentosky |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-12 |
Journal Detail:
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Title: Journal of attention disorders Volume: - ISSN: 1557-1246 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9615686 Medline TA: J Atten Disord Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Lehigh University, Bethlehem, PA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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