Document Detail

Dosimetric comparison of field in field intensity-modulated radiotherapy technique with conformal radiotherapy techniques in breast cancer.
MedLine Citation:
PMID:  20512546     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The aim of this study was to be able to implement the field-in-field intensity-modulated radiotherapy (FiF) technique in our daily practice for breast radiotherapy. To do this, we performed a dosimetric comparison. MATERIALS AND METHODS: Treatment plans were produced for 20 consecutive patients. FiF plans and conformal radiotherapy (CRT) plans were compared for doses in the planning target volume (PTV), the dose homogeneity index (DHI), doses in irradiated soft tissue outside the target volume (SST), ipsilateral lung and heart doses for left breast irradiation, and the monitor unit counts (MU) required for treatment. Averaged values were compared using Student's t-test. RESULTS: With FiF, the DHI is improved 7.0% and 5.7%, respectively (P < 0.0001) over the bilateral and lateral wedge CRT techniques. When the targeted volumes received 105% and 110% of the prescribed dose in the PTV were compared, significant decreases are found with the FiF technique. With the 105% dose, the SST, heart, and ipsilateral lung doses and the MU counts were also significantly lower with the FiF technique. CONCLUSION: The FiF technique, compared to CRT, for breast radiotherapy enables significantly better dose distribution in the PTV. Significant differences are also found for soft tissue volume, the ipsilateral lung dose, and the heart dose. Considering the decreased MUs needed for treatment, the FiF technique is preferred over tangential CRT.
Tülay Ercan; Sefik Iğdem; Gül Alço; Funda Zengin; Selin Atilla; Maktav Dinçer; Sait Okkan
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-05-29
Journal Detail:
Title:  Japanese journal of radiology     Volume:  28     ISSN:  1867-108X     ISO Abbreviation:  Jpn J Radiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-31     Completed Date:  2010-09-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  283-9     Citation Subset:  IM    
Department of Radiation Oncology, Florence Nightingale Gayrettepe Hospital, Cemil Aslan Güder Sok 8, Gayrettepe, Istanbul, 34340, Turkey.
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MeSH Terms
Breast Neoplasms / radiography,  radiotherapy*
Heart / radiation effects
Lung / radiation effects
Radiotherapy Dosage
Radiotherapy, Conformal / methods*
Radiotherapy, Intensity-Modulated / methods*
Tomography, X-Ray Computed
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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