Document Detail

Dose-response effects of medical exercise therapy in patients with patellofemoral pain syndrome: a randomised controlled clinical trial.
MedLine Citation:
PMID:  23219636     Owner:  NLM     Status:  Publisher    
OBJECTIVES: To evaluate two different therapeutic exercise regimens in patients with patellofemoral pain syndrome (PFPS). DESIGN: Multicentre, randomised controlled clinical trial. SETTING: Three primary healthcare physiotherapy clinics. PARTICIPANTS: Forty-two patients with PFPS were assigned at random to an experimental group or a control group. Forty participants completed the study. INTERVENTIONS: Both groups received three treatments per week for 12 weeks. The experimental group received high-dose, high-repetition medical exercise therapy, and the control group received low-dose, low-repetition exercise therapy. The groups differed in terms of number of exercises, number of repetitions and sets, and time spent performing aerobic/global exercises. MAIN OUTCOME MEASURES: Outcome parameters were pain (measured using a visual analogue scale) and function [measured using the step-down test and the modified Functional Index Questionnaire (FIQ)]. RESULTS: At baseline, there were no differences between the groups. After the interventions, there were statistically significant (P<0.05) and clinically important differences between the groups for all outcome parameters, all in favour of the experimental group: -1.6 for mean pain [95% confidence interval (CI) -2.4 to -0.8], 6.5 for step-down test (95% CI 3.8 to 9.2) and 3.1 for FIQ (95% CI 1.2 to 5.0). CONCLUSION: The results indicate that exercise therapy has a dose-response effect on pain and functional outcomes in patients with PFPS. This indicates that high-dose, high-repetition medical exercise therapy is more efficacious than low-dose, low-repetition exercise therapy for this patient group. Registered on (identifier: NCT01290705).
Berit Osterås; Håvard Osterås; Tom Arild Torstensen; Ottar Vasseljen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-24
Journal Detail:
Title:  Physiotherapy     Volume:  -     ISSN:  1873-1465     ISO Abbreviation:  Physiotherapy     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401223     Medline TA:  Physiotherapy     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.
Department of Physiotherapy, Faculty of Health Education and Social Work, Sør-Trøndelag University College, Trondheim, Norway. Electronic address:
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