| Dose effects of relaxation practice on immune responsesin women newly diagnosed with breast cancer: an exploratory study. | |
| | |
MedLine Citation:
|
PMID: 21531674 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Purpose/Objectives: To determine the dose effects of relaxation practice on immune responses and describe the types of relaxation techniques preferred and the extent of relaxation practice over 10 months.Design: Descriptive, prospective, repeated measures.Setting: An interdisciplinary breast clinic at a university-affiliated comprehensive cancer center in the United States.Sample: 49 women with newly diagnosed breast cancer and undergoing adjuvant therapy who participated in a stress management intervention.Methods: Relaxation practice was assessed twice a month for 10 months with immune measurements (e.g., natural killer cell activity; lymphocyte proliferation; interferon [IFN]-g; interleukin [IL]-2, -4, -6, and -10) at the beginning and end of 10-month practice.Main Research Variables: Relaxation practice (representing the concepts of stress and adherence), relaxation technique, and immune response.Findings: After adjusting for covariates, the extent of relaxation practice significantly contributed to the variance of natural killer cell activity, lymphocyte proliferation, IL-4, and IL-10 responses in a positive direction; the higher the relaxation practice, the higher the immune responses. In comparison, IFN-g, IL-2, and IL-6 responses were not affected. The deep-breathing method was most preferred by participants, followed by progressive relaxation and imagination or visualization. The mean weekly frequency of relaxation practice was 5.29 (SD = 3.35), and the mean duration of relaxation practice was 19.16 (SD = 10.81) minutes per session.Conclusions: Persistent relaxation practice may have positive effects on multiple immune responses in a dose-dependent manner.Implications for Nursing: Allowing the choice of preferred techniques and emphasizing the importance of long-term adherence, a relaxation program may need to be routinely offered to women under high stress. |
| | |
Authors:
|
Duck-Hee Kang; Traci McArdle; Na-Jin Park; Michael T Weaver; Barbara Smith; John Carpenter |
Related Documents
:
|
15158284 - Abatement cost curves: a viable management tool for enabling the achievement of win-win... 20925154 - Explaining the unexpected success of the smoking ban in italy: political strategy and t... 19756244 - Strategies for therapeutic repair: the "r(3)" regenerative medicine paradigm. 21073574 - Impact of leadership development on emotional health in healthcare managers. 8144804 - Attitudes and opinions of dietetics professionals toward cost-benefit and cost-effectiv... 11296824 - Fleas (siphonaptera) collected from small mammals in southern viet nam in 1997-1998. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Oncology nursing forum Volume: 38 ISSN: 1538-0688 ISO Abbreviation: Oncol Nurs Forum Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-05-02 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7809033 Medline TA: Oncol Nurs Forum Country: United States |
Other Details:
|
Languages: eng Pagination: E240-52 Citation Subset: IM; N |
Affiliation:
|
Center for Nursing Research, University of Texas-Houston. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nurses' Perceptions and Experiences With End-of-Life Communication and Care.
Next Document: Examining emotional outcomes among a multiethnic cohort of breast cancer survivors.