Document Detail

Dorsal hippocampus function in learning and expressing a spatial discrimination.
MedLine Citation:
PMID:  16585789     Owner:  NLM     Status:  MEDLINE    
Learning to discriminate between spatial locations defined by two adjacent arms of a radial maze in the conditioned cue preference paradigm requires two kinds of information: latent spatial learning when the rats explore the maze with no food available, and learning about food availability in two spatial locations when the rats are then confined in one arm with food and the other with no food. Previous research showed that a functional dorsal hippocampus is not required for latent learning. The present experiments show that it is required for learning about food availability, and during retrieval of both types of information.
Norman M White; Stephane Gaskin
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Learning & memory (Cold Spring Harbor, N.Y.)     Volume:  13     ISSN:  1072-0502     ISO Abbreviation:  Learn. Mem.     Publication Date:    2006 Mar-Apr
Date Detail:
Created Date:  2006-04-04     Completed Date:  2006-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9435678     Medline TA:  Learn Mem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  119-22     Citation Subset:  IM    
Department of Psychology, McGill University, Montreal, Quebec H3A 1B1, Canada.
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MeSH Terms
Analysis of Variance
Conditioning (Psychology) / drug effects,  physiology
Discrimination Learning / drug effects,  physiology*
GABA Agonists / administration & dosage
Hippocampus / drug effects,  physiology*
Maze Learning / drug effects,  physiology*
Muscimol / administration & dosage
Reinforcement (Psychology)
Space Perception / drug effects,  physiology*
Spatial Behavior / drug effects,  physiology*
Reg. No./Substance:
0/GABA Agonists; 2763-96-4/Muscimol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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