| Doppler umbilical and uterine flow waveforms in severe pregnancy hypertension. | |
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MedLine Citation:
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PMID: 2180475 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Doppler studies of the umbilical and uteroplacental bed arterial flow velocity waveforms were performed in a series of women suffering from severe proteinuric pregnancy hypertension. Ninety-five women were studied and the mean interval between the last study and delivery was 1.4 days. An abnormally elevated umbilical artery systolic:diastolic (AB) ratio was present in 61 (64%) of the women. All 10 perinatal deaths were associated with pregnancies with an abnormal umbilical artery AB ratio. An elevated umbilical artery AB ratio was significantly associated with small-for-gestation and neonatal morbidity. Infants associated with extremely high umbilical artery AB ratios (greater than or equal to 99th centile) spent twice as long in the neonatal nursery as those with a lower value. There was no relation between the duration of hypertension and the umbilical study result. The uteroplacental bed artery flow velocity waveform did not correlate with fetal or neonatal mortality or morbidity. Patients with abnormal uteroplacental AB ratios also had abnormal umbilical artery AB ratios. We conclude that an abnormal fetal umbilical artery Doppler flow velocity waveform correlates with adverse fetal outcome in severe proteinuric pregnancy hypertension and suggest that the associated placental lesion may precede the maternal hypertension. |
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Authors:
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B J Trudinger; C M Cook |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of obstetrics and gynaecology Volume: 97 ISSN: 0306-5456 ISO Abbreviation: Br J Obstet Gynaecol Publication Date: 1990 Feb |
Date Detail:
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Created Date: 1990-05-08 Completed Date: 1990-05-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503752 Medline TA: Br J Obstet Gynaecol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 142-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Sydney, Westmead Hospital, NSW, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Blood Flow Velocity Female Fetal Growth Retardation / physiopathology Gestational Age Humans Hypertension / physiopathology* Infant, Newborn Infant, Small for Gestational Age Pregnancy Pregnancy Complications, Cardiovascular / physiopathology* Pregnancy Outcome Time Factors Ultrasonography* Umbilical Arteries / physiopathology* Uterus / blood supply* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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