Document Detail


Doppler ultrasonographic and scintigraphic assessment of an auxiliary heterotopic liver transplantation with portal vein arterialization in pigs.
MedLine Citation:
PMID:  16647519     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Our aim was to evaluate liver graft integrity and function using scintigraphy and ultrasonography in a porcine model of auxiliary heterotopic liver transplantation with portal vein arterialization (AHLT-PVA). MATERIALS AND METHODS: Using Doppler ultrasonography we evaluated eight AHLT-PVA by parenchymal echogenicity, portal and arterial anatomy, and portal and biliary system flow. Two types of scintigraphy were performed: microaggregated human albumin colloid scintigraphy and diisopropyl iminodiacetic acid (DISIDA) scintigraphy, both labeled with 99mTc. RESULTS: The animals were distributed into two groups. The first group consisted of three animals with clinical suspicion of graft dysfunction, in which the ultrasonographic study revealed areas of parenchymal destructuring. In the scintigraphic study, heterogenous uptake was observed; there was no uptake in one animal. Necropsy of these three animals revealed areas of graft necrosis. The second group consisted of five animals with good clinical evolutions, in which the ultrasonographic study showed portal dilation, portal flow with arterial spiculations, and homogenous echogenicity of the hepatic parenchyma. The scintigraphic study revealed homogenous uptake by the graft and an elimination speed of the hepatobiliary agent similar to that of the native liver. CONCLUSIONS: An heterogenous echostructure of the graft provided a sign of poor prognosis indicating necrosis in the same way as heterogenous uptake or nonuptake of radioisotope upon scintigraphy. Scintigraphy is a good method to evaluate biliary function and bile elimination. In an AHLT-PVA, the main ultrasound findings derived from arterialization were dilation of the portal system and portal flow with arterial spiculations.
Authors:
O M Fernández-Rodríguez; A Ríos; J L Navarro; J A Pons; C G Palenciano; R Mota; J J Berenguer; F Mulero; J Contreras; C Conesa; P Ramírez; T Fuente; P Parrilla;
Related Documents :
7209779 - Thrombosis of the portal vein following splenectomy for myeloid metaplasia.
19826629 - Effective endovascular stenting of malignant portal vein obstruction in pancreatic cancer.
19499309 - Successful portal-systemic shunt occlusion of a direct shunt between the inferior mesen...
9606789 - Adrenal cortical carcinoma associated with a splenic vein tumor thrombus.
6465809 - Influence of dryness of the vessel on its patency.
1853809 - Diagnosis of portal vein thrombosis: value of color doppler imaging.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  38     ISSN:  0041-1345     ISO Abbreviation:  Transplant. Proc.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-05-01     Completed Date:  2006-08-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  963-6     Citation Subset:  IM    
Affiliation:
Unit of Experimental Surgery, Department of Surgery, Arrixaca University Hospital, Murcia, Spain. olga005ma@terra.es
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Liver / radionuclide imaging,  ultrasonography*
Liver Transplantation / methods*,  physiology
Models, Animal
Portal Vein / surgery*
Swine
Transplantation, Heterotopic
Ultrasonography, Doppler

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Compensatory lung growth in autologous lobar implant: experimental study in dogs.
Next Document:  Bloodstream cells phenotypically identical to human mesenchymal bone marrow stem cells circulate in ...