Document Detail

Doppler flow measurements and histomorphology of the placental bed in uteroplacental insufficiency.
MedLine Citation:
PMID:  1501057     Owner:  NLM     Status:  MEDLINE    
For the first time histomorphological findings of the uteroplacental vessels were correlated with Doppler flow parameters of this vascular area in a combined study. The study group consisted of 58 women with a pregnancy-induced hypertension or an otherwise presumed uteroplacental perfusion impairment delivered by cesarean section. The control group included 50 healthy pregnancies, delivered by cesarean section due to presentation anomalies or failure to proceed. After removal of the placenta a placental bed biopsy containing the uteroplacental vessels of the decidual and inner myometrial layer was taken. The occurrence of accepted histological signs of low uteroplacental perfusion was compared to Doppler flow velocity wave forms in uteroplacental arteries. The accuracy of doppler-sonographic findings of uteroplacental circulatory impairment confirmed by the histomorphological results was high, even in cases not complicated by hypertension. The good accordance of Doppler flow parameters with morphological findings offers new perspectives for differentiated insights in pregnancy courses with and without signs of uteroplacental insufficiency.
H J Voigt; V Becker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  20     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  1992  
Date Detail:
Created Date:  1992-09-15     Completed Date:  1992-09-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  139-47     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Erlangen-Nuernberg, Fed. Rep. of Germany.
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MeSH Terms
Arteries / pathology
Gestational Age
Hypertension / etiology,  pathology*,  ultrasonography
Placenta / blood supply*,  pathology,  ultrasonography
Placental Insufficiency / pathology*,  ultrasonography
Pregnancy Complications, Cardiovascular / pathology*,  ultrasonography
Ultrasonography, Prenatal*
Uterus / blood supply

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