Document Detail

Doppler evaluation of the thyroid in pediatric goiter.
MedLine Citation:
PMID:  14705174     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The aim of this study was to identify any changes in Doppler parameters in the thyroid arteries of pediatric patients with a clinical diagnosis of goiter living in an area where goiter is endemic. PATIENTS AND METHODS: In this prospective study, 20 pediatric patients with simple endemic goiter and 20 age-matched healthy subjects underwent sonographic examination. The resistance index (RI) and peak systolic velocity (PSV) on duplex sonography were measured from the inferior thyroid arteries, and the thyroid gland volume was recorded. Serum thyrotropin, free T3 hormone, and free T4 hormone levels were measured in both groups. RESULTS: The mean thyroid volume (+/- standard deviation) was significantly higher in the patients than in the healthy subjects (7.2 +/- 1.4 ml versus 3.2 +/- 1.1 ml; p < 0.01). The mean RI values for the thyroid arteries were significantly lower in the patient than in the control group (0.58 versus 0.70, respectively; p < 0.05). The mean PSV of the thyroid arteries was significantly higher for the patients than for the healthy subjects (mean, 36.7 cm/second versus 18.3 cm/second, respectively; p < 0.05). There was no correlation between the Doppler parameters and any of the hormone levels evaluated. CONCLUSIONS: In the arteries supplying the thyroid gland in a pediatric population, RIs were lower and PSVs higher in the patients with diffuse goiter than in the healthy control group. We discuss iodine deficiency as a possible mechanism for these changes.
Kamran Mahmutyazicioğlu; Mehmet Turgut
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  32     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-01-05     Completed Date:  2004-05-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  24-8     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley Periodicals, Inc.
Department of Radiology, Inonu University Medical Faculty, 44300 Malatya, Turkey.
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MeSH Terms
Goiter / ultrasonography*
Prospective Studies
Reference Values
Thyroid Function Tests
Thyroid Gland / anatomy & histology,  blood supply*,  ultrasonography
Thyroid Hormones / blood
Ultrasonography, Doppler
Reg. No./Substance:
0/Thyroid Hormones

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