Document Detail

Doppler echocardiographic assessment of changes in the central circulation of the fetal sheep induced by maternal oxygen administration.
MedLine Citation:
PMID:  7841692     Owner:  NLM     Status:  MEDLINE    
Eleven fetal sheep were studied to investigate if Doppler echocardiography could document redistribution of blood flow during maternal oxygen administration. Velocities through the pulmonary valve, aortic valve, common brachiocephalic trunk, aortic arch, descending aorta, umbilical and carotid artery were recorded before, during and after oxygen was delivered to the ewe by face mask. Indices of cardiac performance (shortening fraction, velocity of fiber shortening and systolic time intervals) were also obtained. The aortic arch was the only recording site where significant changes in mean velocity related to oxygen administration and withdrawal were demonstrated (p < 0.01). Changes in the velocity waveform suggesting an increase in cerebral vascular resistance during oxygen administration were found in the carotid artery. Thus, using Doppler velocimetry, the carotid artery and the aortic arch (equivalent to the human aortic isthmus) appear to be suitable sites to document changes induced by maternal oxygen administration.
S E Sonesson; J C Fouron; G Teyssier; P Bonnin
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  83     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-03-07     Completed Date:  1995-03-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  1007-11     Citation Subset:  IM    
Department of Pediatrics, St Justine Hospital, University of Montreal, Canada.
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MeSH Terms
Blood Circulation / drug effects*
Carotid Arteries / physiology
Cerebrovascular Circulation / drug effects
Echocardiography, Doppler*
Fetus / blood supply*,  drug effects
Hemodynamics / drug effects
Maternal-Fetal Exchange
Oxygen / pharmacology*
Pregnancy, Animal / physiology*
Ultrasonography, Prenatal*
Vascular Resistance / drug effects
Ventricular Function / physiology*
Reg. No./Substance:

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