Document Detail


Doppler echocardiographic analysis of cardiac flow during the Mueller manoeuver.
MedLine Citation:
PMID:  1907558     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The inspiration against a closed airway, the Mueller manoeuver, leads to a negative intrathoracic pressure. It is controversially discussed whether this is causing an augmentation of right heart murmurs. There is only limited knowledge on the temporal relationship of the negative intrathoracic pressure with right and left ventricular filling and stroke volume. To investigate this relationship, the flow through the mitral, aortic, tricuspid and pulmonary valves was studied continuously by Doppler echocardiography during a standardized Mueller manoeuver in 15 healthy subjects (age 45 +/- 10 years). Five heart beats after the initiation of the manoeuver, flow through the mitral and aortic valve decreased 12.2 +/- 7.2% (P less than 0.001) and 10.1 +/- 6.6% (P less than 0.001), respectively. A transient increase of 15.1 +/- 9.2% (P less than 0.001) in tricuspid flow was followed by a 14.3 +/- 9.8% (P less than 0.005) increase of flow through the pulmonary artery. Ten heart beats after the initiation of the Mueller manoeuver, flow through the pulmonary artery again reached baseline, while tricuspid flow remained below baseline values. In contrast to previous studies, our results indicate that the Mueller manoeuver causes a small and transient increase in right ventricular stroke volume which is unlikely to cause a marked augmentation in right heart murmurs.
Authors:
S Andreas; G S Werner; G Sold; V Wiegand; H Kreuzer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of clinical investigation     Volume:  21     ISSN:  0014-2972     ISO Abbreviation:  Eur. J. Clin. Invest.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-09-11     Completed Date:  1991-09-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0245331     Medline TA:  Eur J Clin Invest     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  72-6     Citation Subset:  IM    
Affiliation:
Department of Cardiology and Pulmonary, University of Göttingen, FRG.
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MeSH Terms
Descriptor/Qualifier:
Adult
Coronary Circulation / physiology*
Echocardiography, Doppler*
Female
Humans
Male
Middle Aged
Pulmonary Circulation / physiology
Respiratory Mechanics / physiology
Stroke Volume / physiology
Ventricular Function, Left / physiology
Ventricular Function, Right / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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