| Doppler echocardiographic analysis of cardiac flow during the Mueller manoeuver. | |
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MedLine Citation:
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PMID: 1907558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The inspiration against a closed airway, the Mueller manoeuver, leads to a negative intrathoracic pressure. It is controversially discussed whether this is causing an augmentation of right heart murmurs. There is only limited knowledge on the temporal relationship of the negative intrathoracic pressure with right and left ventricular filling and stroke volume. To investigate this relationship, the flow through the mitral, aortic, tricuspid and pulmonary valves was studied continuously by Doppler echocardiography during a standardized Mueller manoeuver in 15 healthy subjects (age 45 +/- 10 years). Five heart beats after the initiation of the manoeuver, flow through the mitral and aortic valve decreased 12.2 +/- 7.2% (P less than 0.001) and 10.1 +/- 6.6% (P less than 0.001), respectively. A transient increase of 15.1 +/- 9.2% (P less than 0.001) in tricuspid flow was followed by a 14.3 +/- 9.8% (P less than 0.005) increase of flow through the pulmonary artery. Ten heart beats after the initiation of the Mueller manoeuver, flow through the pulmonary artery again reached baseline, while tricuspid flow remained below baseline values. In contrast to previous studies, our results indicate that the Mueller manoeuver causes a small and transient increase in right ventricular stroke volume which is unlikely to cause a marked augmentation in right heart murmurs. |
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Authors:
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S Andreas; G S Werner; G Sold; V Wiegand; H Kreuzer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of clinical investigation Volume: 21 ISSN: 0014-2972 ISO Abbreviation: Eur. J. Clin. Invest. Publication Date: 1991 Feb |
Date Detail:
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Created Date: 1991-09-11 Completed Date: 1991-09-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0245331 Medline TA: Eur J Clin Invest Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 72-6 Citation Subset: IM |
Affiliation:
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Department of Cardiology and Pulmonary, University of Göttingen, FRG. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Coronary Circulation / physiology* Echocardiography, Doppler* Female Humans Male Middle Aged Pulmonary Circulation / physiology Respiratory Mechanics / physiology Stroke Volume / physiology Ventricular Function, Left / physiology Ventricular Function, Right / physiology |
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