Document Detail


Doppler echocardiograph evaluation of pulmonary hypertension in patients undergoing hemodialysis.
MedLine Citation:
PMID:  17014511     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulmonary hypertension (PH) has been reported in hemodialysis (HD) patients, but data regarding its incidence and mechanisms are scarce. The aims of this study was to evaluate the prevalence of unexplained PH in long-term HD patients, and to examine some possible etiologic factors for its occurrence. The prevalence of PH was estimated by Doppler echocardiography in a cohort of 86 stable patients on HD via arteriovenous access for more than 12 months. All the patients underwent full clinical evaluation, chest radiography, and a standard 12-lead echocardiograph. Laboratory investigation included a mean of 12 months (serum calcium, phosphorus, parathormone (PTH), alkaline phosphatase, lipids, and hemoglobin). Pulmonary hypertension was defined as pulmonary artery systolic pressure >35 mmHg as determined by Doppler echocardiography using the modified Bernoulli equation. Pulmonary hypertension was detected in 23 patients (26.74%). Of those with PH, left ventricular hypertrophy was seen in 13 patients (56.52%), and valvular calcifications in 6 patients (26.08%). There were no significant differences between both groups with regard to age, sex, duration of dialysis, shunt location, and all the biological parameters of the study. The presence of PH was not related to the level of PTH, or the severity of other metabolic abnormalities. This study demonstrates a high prevalence of PH among patients with ESRD receiving long-term HD via surgical arteriovenous access. The role of the vascular access, anemia, or secondary hyperparathyroidism as the etiology of PH in HD patients did not hold in this study.
Authors:
Faissal Tarrass; Meryem Benjelloun; Ghislaine Medkouri; Khadija Hachim; Mohamed Gharbi Benghanem; Benyounes Ramdani
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hemodialysis international. International Symposium on Home Hemodialysis     Volume:  10     ISSN:  1492-7535     ISO Abbreviation:  Hemodial Int     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-03     Completed Date:  2006-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101093910     Medline TA:  Hemodial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  356-9     Citation Subset:  IM    
Affiliation:
Department of Nephrology and Dialysis, IBN ROCHD University Hospital Center, Casablanca, Morrocco. faissal76@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Calcinosis / etiology,  ultrasonography
Echocardiography, Doppler
Female
Heart Valve Diseases / etiology,  ultrasonography
Humans
Hypertension, Pulmonary / etiology*,  ultrasonography*
Hypertrophy, Left Ventricular / etiology,  ultrasonography
Kidney Failure, Chronic / complications,  therapy,  ultrasonography
Male
Middle Aged
Parathyroid Hormone / blood
Renal Dialysis*
Risk Factors
Chemical
Reg. No./Substance:
0/Parathyroid Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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