Document Detail

A Doppler-based evaluation of peripheral lower limb arterial insufficiency in diabetes mellitus.
MedLine Citation:
PMID:  20141688     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the frequency, level and flow patterns of lower limb arterial insufficiency in diabetic patients on Doppler ultrasound study. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Radiology Department, Civil Hospital, Karachi, from February 2007 to September 2008. METHODOLOGY: One hundred adult diabetic patients with suspected peripheral vascular insufficiency irrespective of gender were included. Demographic data, presenting complaints, treatment history, and level of HbA1c were recorded. Doppler evaluated arterial status and ankle brachial index (ABI) were recorded on proforma. Statical analysis were done on SPSS version 12. RESULTS: The mean HbA1c was 8.4+/-1.4 gm/dl, a majority of 77% having a controlled level of <10mg/dl. Arterial insufficiency on Doppler ultrasound was documented in 62% (p=0.016) and the dorsalis paedis artery was the predominant site of stenosis (24%). Spectral broadening and biphasic flow were salient features. The mean value of resistive index in stenotic cases was 0.563+/-0.16 with a mean velocity difference of 0.37+/-0.29 m/s (p<0.001) at the site of stenosis. CONCLUSION: Peripheral vascular insufficiency was a significant finding in patients having diabetes for an average of 9.8 years, even in the presence of controlled HbA1c. The dorsalis paedis was the commonest site of involvement. The insufficiency was moderate with a biphasic flow pattern in a majority of cases. Difference in resistive index and flow velocities at and above the site of stenosis provided an important clue to the diagnosis of level of stenosis that helps in planning limb salvage management.
Riffat Shaheen; Saba Sohail
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  20     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-09     Completed Date:  2010-03-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  22-5     Citation Subset:  IM    
Department of Radiology, Dow University of Health Sciences and Civil Hospital, Karachi.
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MeSH Terms
Arteries / pathology
Constriction, Pathologic
Diabetic Angiopathies / ultrasonography*
Leg / blood supply*
Middle Aged
Peripheral Vascular Diseases / ultrasonography*
Ultrasonography, Doppler

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