Document Detail


Doppler-based diagnosis of restenosis after femoropopliteal percutaneous transluminal angioplasty: sensitivity and specificity of the ankle/brachial pressure index versus changes in absolute pressure values.
MedLine Citation:
PMID:  10063941     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to investigate the sensitivity and specificity of changes of the ankle/brachial pressure index (ABI) and changes in absolute ankle pressure values to detect restenosis in patients who underwent femoropopliteal percutaneous transluminal angioplasty (PTA). In total, 171 patients were followed up prospectively for 12 months; sensitivity and specificity of Doppler-based diagnosis were calculated with duplex scanning as the gold standard. The criteria for restenosis were: (1) a loss of 50% of the ABI increase or (2) loss of 50% of the absolute ankle systolic pressure, gained by PTA. For both criteria, different cut-off points (minimum increase of ABI or ankle pressure gained by PTA) were evaluated. The overall sensitivity and specificity of the ABI criterion was 67% and 80%, respectively. The introduction of cut-off points (the minimum ABI increase gained by PTA), ranging between > or = 0.13 and > or = 0.35, did not markedly improve the results. The overall sensitivity and specificity of the absolute ankle pressure criterion again was poor (59% and 81%). With the introduction of cut-off points (the minimum increase of absolute ankle pressure gained by PTA) ranging between > or = 15 mm Hg and > or = 20 mm Hg, the sensitivity and specificity of the criterion improved to acceptable 92% and 96%, respectively. It is concluded, that in the long-term follow-up of PTA patients, the "loss of 50% ankle pressure" criterion will detect restenosis with reasonable accuracy in those patients, in whom an increase in systolic ankle pressure > or = 20 mm Hg is warranted.
Authors:
D Radak; K H Labs; K A Jäger; M Bojić; A D Popović
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  50     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-03-16     Completed Date:  1999-03-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  111-22     Citation Subset:  IM    
Affiliation:
Dedinje Cardiovascular Institute, Belgrade University Medical School, Yugoslavia.
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MeSH Terms
Descriptor/Qualifier:
Aged
Angioplasty, Balloon*
Ankle / blood supply*
Arm / blood supply*
Arteriosclerosis / therapy*,  ultrasonography
Blood Pressure / physiology*
Disease Progression
Female
Femoral Artery / ultrasonography*
Follow-Up Studies
Humans
Hyperplasia
Male
Popliteal Artery / ultrasonography*
Prospective Studies
Recurrence
Sensitivity and Specificity
Systole
Tunica Intima / ultrasonography
Ultrasonography, Doppler*
Ultrasonography, Doppler, Duplex

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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