Document Detail

Doppler assessment of the effects of isometric stress on left ventricular filling in hypertensive young adults.
MedLine Citation:
PMID:  2596739     Owner:  NLM     Status:  MEDLINE    
Doppler interrogation at the in-flow of the left ventricle was used to test the effects of isometric stress on ventricular filling in 7 hypertensive subjects with mild to moderate left ventricular hypertrophy, aged forty-two +/- seven years, compared with 9 matched healthy control males. In the hypertensive patients at rest, peak early diastolic (E) velocity was lower, and atrial (A) velocity higher, with lower E/A peak velocity ratios than in normals (p less than 0.05). These differences were more accentuated during isometric stress. Atrial filling fractions were higher in hypertensives (37 +/- 6%) than in normals (24 +/- 7%) at rest, p less than 0.05, and this difference increased during isometric stress (44 +/- 9% versus 30 +/- 11%). Thus, isometric stress accentuated the reliance of left ventricular filling on atrial contribution and may be applied for the detection of early ventricular filling abnormalities in patients with mild hypertension. The systolic blood pressure and the hypertrophic process were both important determinants of left ventricular diastolic filling.
E G Abinader; D Sharif; M Sagiv; E Goldhammer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Angiology     Volume:  40     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-01-17     Completed Date:  1990-01-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1052-7     Citation Subset:  IM    
Heart Institute, Haifa Medical Center (Rothschild), Faculty of Medicine, Technion-Israel Institute.
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MeSH Terms
Blood Pressure
Echocardiography, Doppler*
Heart / physiopathology*
Heart Rate
Hypertension / physiopathology*
Isometric Contraction*
Muscle Contraction*
Physical Exertion*
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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