Document Detail


Doppler analysis of uterine perfusion and ovarian stromal blood flow in polycystic ovary syndrome.
MedLine Citation:
PMID:  19232596     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate blood flow velocity in the ovarian stromal artery and uterine artery in women with polycystic ovary syndrome (PCOS) and to correlate these velocities with clinical and biochemical parameters. METHODS: A prospective study was carried out in 55 patients with PCOS and 42 age-matched women who did not have PCOS. Clinical, biochemical, and hormonal characteristics, and utero-ovarian Doppler ultrasound blood flow parameters were determined, and correlations between the parameters were evaluated. RESULTS: Ovarian stromal blood flow was higher (P<0.01) and uterine perfusion was lower (P<0.01) in women with PCOS compared with women who did not have PCOS. Ovarian stromal artery pulsatility index (PI) was inversely correlated with levels of dehydroepiandrosterone sulfate (DHEAS) and insulin-like growth factor-1, and with the luteinizing hormone/follicle-stimulating hormone ratio. There was a positive correlation between uterine artery PI and DHEAS level. CONCLUSION: Doppler analysis of the uterine and intraovarian arteries may provide additional information about the etiopathogenesis of PCOS and partly explain the clinical implications of the condition.
Authors:
Ertan Adali; Ali Kolusari; Fulya Adali; Recep Yildizhan; Mertihan Kurdoglu; Hanim Guler Sahin
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Publication Detail:
Type:  Journal Article     Date:  2009-02-20
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  105     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-13     Completed Date:  2009-07-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  154-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Yuzuncu Yil University, Van, Turkey. ertanadali@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Dehydroepiandrosterone Sulfate / blood
Female
Follicle Stimulating Hormone / blood
Humans
Luteinizing Hormone / blood
Ovary / blood supply*,  ultrasonography
Polycystic Ovary Syndrome / blood,  physiopathology*,  ultrasonography
Prospective Studies
Regional Blood Flow
Somatomedins / metabolism
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Pulsed
Uterus / blood supply*,  ultrasonography
Young Adult
Chemical
Reg. No./Substance:
0/Somatomedins; 651-48-9/Dehydroepiandrosterone Sulfate; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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