| Doppler ultrasonography for the noninvasive measurement of uterine artery volume blood flow through gestation in the pregnant sheep. | |
| | |
MedLine Citation:
|
PMID: 19767542 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Accurate noninvasive quantification of volume blood flow in the uterine arteries (UtAs) would have clinical and research benefits. We evaluated the correlation and agreement between uterine artery volume blood flow (UtABF) as calculated (cUtABF) from color/pulsed-wave Doppler acquisitions and that measured (mUtABF) by bilateral perivascular transit-time flow probes in 6 pregnant sheep at 2 gestational ages. Out of 22 Doppler acquisitions, 19 were successful. The overall correlation between cUtABF and mUtABF was 0.55 (n = 19, P = .01). Calculated UtABF and mUtABF were significantly correlated in late gestation (n = 11, r = 0.71, P = .01) but not at mid-gestation (n = 8, r = .02, P = .96). By Bland-Altman analysis, the mean cUtABF/mUtABF was 1.15 with 95% limit of agreement (-0.26 to 2.56), similar to results previously achieved using power/pulsed-wave Doppler. Despite the acceptable correlation, the limits of agreement between Doppler and transit-time flow probe measurements remain wide. This makes Doppler ultrasonography less than a desirable method to quantify UtABF in studies where accurate quantification is required. |
| | |
Authors:
|
Khalil N Abi-Nader; Vedanta Mehta; Victoria Wigley; Elisa Filippi; Berrin Tezcan; Michael Boyd; Donald M Peebles; Anna L David |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-09-18 |
Journal Detail:
|
Title: Reproductive sciences (Thousand Oaks, Calif.) Volume: 17 ISSN: 1933-7205 ISO Abbreviation: Reprod Sci Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2010-01-14 Completed Date: 2010-03-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101291249 Medline TA: Reprod Sci Country: United States |
Other Details:
|
Languages: eng Pagination: 13-9 Citation Subset: IM |
Affiliation:
|
Fetal Medicine Unit, Elizabeth Garrett Anderson Institute for Women's Health, University College London and University College London Hospitals NHS Foundation Trust, London WC1E 6HX, United Kingdom. abinaderk@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Volume / physiology* Female Pregnancy Regional Blood Flow / physiology* Regression Analysis Sheep Ultrasonography, Doppler / methods* Ultrasonography, Prenatal / methods Uterine Artery / physiology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Effect of Oxytocin and an Oxytocin Antagonist on the Human Myometrial Proteome.
Next Document: Menstrual Cycle Abnormalities Among Cosmetologists: The Reproductive Outcomes in Salon Employees (RO...