| Dopamine receptors in hypertension. | |
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MedLine Citation:
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PMID: 11687863 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is increased awareness of the role of dopamine in cardiovascular function, renal function and systemic blood pressure regulation. Growing evidence indicates that each of the five dopamine receptor subtypes participates in the regulation of blood pressure by mechanisms distinct for that particular subtype. Some dopamine receptors regulate blood pressure by influencing the central and peripheral nervous system, while others influence renal function and release of renin, aldosterone and vasopressin. This review summarizes the physiology and pathophysiology of the peripheral dopaminergic system and our current understanding of the role of individual dopamine receptors in the pathophysiology of human essential hypertension. |
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Authors:
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M J Bek; G M Eisner; R A Felder; P A Jose |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: The Mount Sinai journal of medicine, New York Volume: 68 ISSN: 0027-2507 ISO Abbreviation: Mt. Sinai J. Med. Publication Date: 2001 Nov |
Date Detail:
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Created Date: 2001-11-05 Completed Date: 2001-12-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0241032 Medline TA: Mt Sinai J Med Country: United States |
Other Details:
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Languages: eng Pagination: 362-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure
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physiology Humans Hypertension / physiopathology* Receptors, Dopamine / physiology* |
| Grant Support | |
ID/Acronym/Agency:
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DK39308/DK/NIDDK NIH HHS; DK52612/DK/NIDDK NIH HHS; HL 58536/HL/NHLBI NIH HHS; HL3081/HL/NHLBI NIH HHS; HL62211/HL/NHLBI NIH HHS; RR13297/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Dopamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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