| Don't forget other causes of wheeze. ABPA in a boy with asthma. A case report and review of the literature. | |
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MedLine Citation:
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PMID: 20722636 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Allergic bronchopulmonary aspergillosis (ABPA) is a rare pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus. The prevalence is estimated to be about 1-2% in adult patients with asthma and 2-15% in patients with cystic fibrosis. In paediatric patients with asthma, only single case reports on ABPA exist. We report on a 13-year-old boy with allergic asthma complicated by ABPA. Despite the presentation of typical clinical symptoms, it took 6 years before he was diagnosed. The clinical course improved rapidly after ABPA therapy was started, and 12 months after diagnosis, the boy is still free of symptoms. Clinical symptoms of ABPA may be unspecific making a rapid diagnosis difficult in some cases. Conclusion: A delay in diagnosis and treatment increases the risk for irreversible lung damage. Once bronchiectasis has developed, the outcome is unfavourable. Thus, ABPA has to be considered in patients whose asthma remains uncontrolled despite adequate therapy. |
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Authors:
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Nicolaus Schwerk; Ulrich Rochwalsky; Folke Brinkmann; Gesine Hansen |
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Publication Detail:
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Type: Journal Article Date: 2010-09-06 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 100 ISSN: 1651-2227 ISO Abbreviation: Acta Paediatr. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: Norway |
Other Details:
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Languages: eng Pagination: 307-10 Citation Subset: IM |
Copyright Information:
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© 2010 The Author(s)/Acta Paediatrica © 2010 Foundation Acta Paediatrica. |
Affiliation:
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Department of Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical school, Hannover, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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