Document Detail

Donor factors in cadaveric renal transplantation.
MedLine Citation:
PMID:  7918168     Owner:  NLM     Status:  MEDLINE    
1. Donor kidney side (left/right) had no significant effect on cadaveric renal allograft survival. 2. Kidneys from male donors had an 83% one-year graft survival rate, compared with 78% for those from female donors. 3. Donor race did not have an effect on renal allograft survival. 4. One-year survival rates for kidneys from very young (< 5 years old) donors and older (> 50 years old) cadaver donors (74%) were significantly poorer than those for kidneys from donors age 6-50 (84%). 5. Donor ABO blood type and Rh factor had no significant effect on renal allograft survival. 6. Cause of death (trauma/nontrauma) had a pronounced effect on cadaveric renal allograft survival. Kidneys from trauma donors (motor vehicle accident, gunshot wound, head injury, etc.) had a significantly higher one-year graft survival rate (84%) than that of kidneys from nontrauma donors (77%). This effect was found to be independent of donor age. 7. Donor past medical history had a significant effect on renal allograft survival. Kidneys from donors with histories of hypertension had slightly poorer graft survival (75%) than those from "normal" donors (80%). Donors with histories of diabetes had significantly lower graft survival; 54.8% at one-year posttransplant. 8. Donor lifestyle factors, including smoking, drinking, drug use, and sexual history, had no significant effect on renal allograft survival. 9. The duration of donor hospitalization (from admission to the time of procurement) had no effect on renal allograft survival. 10. Donor cardiac arrest (in either the field, hospital, or operating room) had no significant effect on renal allograft survival.(ABSTRACT TRUNCATED AT 250 WORDS)
N J Feduska
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical transplants     Volume:  -     ISSN:  0890-9016     ISO Abbreviation:  Clin Transpl     Publication Date:  1993  
Date Detail:
Created Date:  1994-11-10     Completed Date:  1994-11-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8812419     Medline TA:  Clin Transpl     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  351-7     Citation Subset:  IM    
Regional Organ Procurement Agency of Southern California, Los Angeles.
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MeSH Terms
ABO Blood-Group System
Child, Preschool
Continental Population Groups
Epidemiologic Factors
Graft Survival*
Infant, Newborn
Kidney Transplantation / immunology*
Length of Stay
Middle Aged
Risk Factors
Tissue Donors* / statistics & numerical data
Reg. No./Substance:
0/ABO Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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