| Donation frequency of blood donors participating in a prospective cohort study of iron status. | |
| | |
MedLine Citation:
|
PMID: 21658037 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Blood centers are interested in understanding determinants of frequent blood donation. We hypothesized that participation in uncompensated research could result in higher donation rates. STUDY DESIGN AND METHODS: Donation rates for 2425 subjects from six US blood centers enrolled in the Retrovirus Epidemiology Donor Study-II Donor Iron Status Evaluation Study were compared to those of nonenrolled donors (n = 202,383). Over 15 months, we compared mean donation rates and adjusted rate ratios (RRs) between enrolled and nonenrolled for three subgroups, first-time, reactivated, and frequent donors, and donation rates before and after the study enrollment period for frequent donors only. RESULTS: Enrolled donors had higher 15-month mean donation rates than nonenrolled donors (first-time, 1.21 [RR = 1.91]; reactivated, 1.68 [RR = 1.83]; frequent, 3.40 [RR = 1.12]). However, frequent donors donated at approximately the same rate after enrollment as they did before enrollment in the study (3.62 per 15 months [RR = 1.12]). CONCLUSION: Donors enrolled in the study donated at a higher rate than nonenrolled donors, but frequent donors remained consistent in their donation frequency both before and after enrollment. Although increased donation rates could have been causally related to study enrollment, we cannot rule out an enrollment bias whereby more committed donors were more likely to enroll in the study. |
| | |
Authors:
|
Shrein H Bahrami; Anne M Guiltinan; Karen S Schlumpf; Erik Scott; Linda L Banks; Pam D'Andrea; Elizabeth L Hartman; Vibha Vij; David J Wright; Bryan Spencer; Edward L Murphy; |
Related Documents
:
|
12052847 - Nitric oxide modulates superoxide release and peroxynitrite formation in human blood ve... 19291087 - The role of nitric oxide- and prostacyclin-independent vasodilatation in the human cuta... 6118327 - Analogs of phosphatidylcholine: alpha-adrenergic antagonists from the renal medulla. 1874277 - Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on new... 12052847 - Nitric oxide modulates superoxide release and peroxynitrite formation in human blood ve... 12803297 - Hepatic bipolar radiofrequency ablation creates coagulation zones close to blood vessel... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural Date: 2011-01-07 |
Journal Detail:
|
Title: Transfusion Volume: 51 ISSN: 1537-2995 ISO Abbreviation: Transfusion Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-06-10 Completed Date: 2011-08-23 Revised Date: 2012-01-04 |
Medline Journal Info:
|
Nlm Unique ID: 0417360 Medline TA: Transfusion Country: United States |
Other Details:
|
Languages: eng Pagination: 1207-12 Citation Subset: IM |
Copyright Information:
|
© 2010 American Association of Blood Banks. |
Affiliation:
|
Blood Systems Research Institute, San Francisco, California, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Donors / statistics & numerical data* Female Humans Iron / blood* Male Middle Aged Prospective Studies |
| Grant Support | |
ID/Acronym/Agency:
|
N01-HB-47168/HB/NHLBI NIH HHS; N01-HB-47169/HB/NHLBI NIH HHS; N01-HB-47170/HB/NHLBI NIH HHS; N01-HB-47171/HB/NHLBI NIH HHS; N01-HB-47172/HB/NHLBI NIH HHS; N01-HB-47174/HB/NHLBI NIH HHS; N01-HB-47175/HB/NHLBI NIH HHS; N01-HB-57181/HB/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
7439-89-6/Iron |
| Investigator | |
Investigator/Affiliation:
|
J Rios / ; R Benjamin / ; J D Roback / ; R A Sacher / ; S L Wilkinson / ; P M Carey / ; E L Murphy / ; B Custer / ; N Hirschler / ; D Triulzi / ; R Kakaiya / ; J Kiss / ; J Gottschall / ; A Mast / ; J Schulman / ; M King / ; G J Nemo / |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The impact of locus of control and priming on the endowment effect.
Next Document: A validation study of new cryopreservation bags for implementation in a blood and marrow transplant ...