Document Detail


Donation after cardiac death: the potential contribution of an infant organ donor population.
MedLine Citation:
PMID:  20732689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the percentage of deaths in level III neonatal intensive care unit (NICU) settings that theoretically would have been eligible for donation after cardiac death (DCD), as well as the percentage of these who would have been potential DCD candidates based on warm ischemic time.
STUDY DESIGN: We conducted a retrospective study of all deaths in 3 Harvard Program in Neonatology NICUs between 2005 and 2007. Eligible donors were identified based on criteria developed with our transplantation surgeons and our local organ procurement organization. Potential candidates for DCD were then identified based on an acceptable warm ischemic time.
RESULTS: Of the 192 deaths that occurred during the study period, 161 were excluded, leaving 31 theoretically eligible donors. Of these, 16 patients had a warm ischemic time of <1 hour and were potential candidates for DCD of 14 livers and 18 kidneys, and 14 patients had a warm ischemic time of <30 minutes and were potential candidates for DCD of 10 hearts.
CONCLUSIONS: Eight percent of NICU mortalities were potential candidates for DCD. Based on the size of the potential donor pool, establishing an infant DCD protocol for level III NICUs should be considered.
Authors:
Michelle Labrecque; Richard Parad; Munish Gupta; Anne Hansen
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Publication Detail:
Type:  Journal Article; Multicenter Study     Date:  2010-08-21
Journal Detail:
Title:  The Journal of pediatrics     Volume:  158     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-01-06     Revised Date:  2011-01-28    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  31-6     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 Mosby, Inc. All rights reserved.
Affiliation:
Division of Newborn Medicine, Children's Hospital Boston, Boston, MA, USA.
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MeSH Terms
Descriptor/Qualifier:
Death*
Female
Humans
Infant, Newborn
Male
Retrospective Studies
Tissue and Organ Procurement / statistics & numerical data*
Comments/Corrections
Comment In:
J Pediatr. 2011 Jan;158(1):6-8   [PMID:  20869726 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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